The Library
The Ultimate On-line Candida Resource
Glossary    Contact Us
 
   
Browse by Category
Your Are Here >> Library Home > Candida In The Body > Immune System > Modulation of Immune System Responses > The induction of T-suppressor cells with a soluble extract of Candida albicans

Back

We'd love to hear from you - the Candida Library is for you. Let us know if you have any suggestions, ideas or feedback. Click here to email us.

The induction of T-suppressor cells with a soluble extract of Candida albicans

The induction of T-suppressor cells with a soluble extract of Candida albicans
C F Cuff, D D Taub, T J Rogers
Cellular immunology. 01/09/1989; 122(1):71-82.
ISSN: 0008-8749

Abstract

We have previously shown that whole cell preparations of Candida albicans are capable of inducing immunosuppressive B-cell activity both in vivo and in vitro. In an effort to characterize the components of the yeast which manifest this immunomodulatory activity, we have successfully generated a soluble extract with dithiothreitol which exerts immunosuppressive activity. This extract is capable of inducing antigen-nonspecific suppressor cells which inhibit the antibody response of normal cells in coculture. Both primary and secondary antibody responses are suppressed by these cells. Our results also show that the suppressor cell population is a member of the L3T4+ Ly-1+ Lyt-2- T-cell lineage. These results provide evidence that Candida extracts may possess clinically significant immunomodulatory activities.

Abstract from:

http://www.researchgate.net/publication/20628841_The_induction_of_Tsuppressor_
cells_with_a_soluble_extract_of_Candida_albicans



Keywords: The induction of T-suppressor cells with a soluble extract of Candida albicans

Rate This Article:

Related Articles

Antimicrobial efficacy of Curcuma zedoaria extract
Antimicrobial efficacy of Curcuma zedoaria   as...

 
Induction of human neutrophil chemotaxis by Candida albicans
Induction of human neutrophil chemotaxis by Candida...

 
Antagonistic effect of edible mushroom extract on candida albicans growth
Antagonistic effect of edible mushroom extract on candida...