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Velocity of Candida albicans invasion into host tissues.

This is a good article that emphasizes the speed at which candida can spread throughout the body. Within a matter of hours, candida albicans can penetrate the body’s defenses and according to the research presented here, “…cause deep and disseminated mycotic lesions within several days.” While the medical and pharmaceutical fields continually abandon the idea of systemic candida being a common reality, researchers worldwide repeatedly and continuously state just the opposite. As doctors, if we abandon the reality of systemic fungal candida being a commonplace result of antibiotic use, then we’ve abandoned the patient, the ones who need us most. - Dr. Jeffrey McCombs, DC

Velocity of Candida albicans invasion into host tissues.
V. L. Bykov

Keywords:

  • Candia albicans;
  • histopathology;
  • invasion velocity;
  • host tissue;
  • Candida albicans;
  • Histopathologie;
  • Invasionsgeschwindigkeit;
  • Wirtsgewebe

Summary. Using 2 experimental models (candidal vaginitis in leukopenic mice and oral candidosis in neonatal rats) characterized by minimal inflammatory response to the pathogen, the rate of invasive growth of Candida albicans in stratified epi-thelia of mucosal membranes was defined. The pseudomycelium was found to invade animal epi-thelia at an average rate of 2 μm per hour, penetrating the entire epithelial thickness during 24–48 h. These data have been extrapolated to clinical pathology. On the basis of experimental data and by measuring the epithelial thickness in some human mucous membranes, the presumable periods of total epithelial penetration were calculated which may lead to vascular invasion and create the danger of dissemination. For different human mucous membranes these periods ranged from 22 to 59 h. These data emphasize the importance of cellular and tissue defense mechanisms, the inhibition of which may allow the fungi normally found on epithelial surfaces as commensals to invade the host tissues and to cause deep and disseminated mycotic lesions within several days.

Purchase the PDF: http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0507.1991.tb00662.x/abstract




Keywords: Velocity of Candida albicans invasion into host tissues antibiotic use mycotic lesions drjefftop beginner

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