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Fungus Related Disease Questionnaire-7 (FRDQ-7)

Fungus Related Disease Questionnaire-7 (FRDQ-7)

SUMMARY: The following seven questions correlated with improvement after nystatin therapy in a controlled clinical study by Santelmann et al. (2001). Patients first filled out a 70-item questionnaire published by Crook (1995), and were then treated with nystatin. Answers from patients who improved were compared to answers from patients who did not respond to therapy. Researchers concluded that only seven questions from the original 70-item questionnaire predicted a positive response to nystatin in 95% of patients. The final list of seven questions below is a scientifically validated screening tool, not a diagnostic test.

0 = none
1 = occasional or mild
2 = frequent or moderately severe
3 = severe or disabling

1.   Have you, at any time in your life, taken broad spectrum antibiotics? (0 or 3)
2.   Have you taken tetracycline or other broad spectrum antibiotics for
      one month or longer? (0 or 3)
3.   Are your symptoms worse on damp, muggy days or in moldy places? (0 or 3)
4.   Do you crave sugar? (0 or 3)
5.   Do you have a feeling of being "drained?” (0, 1, 2 or 3)
6.   WOMEN:  Are you bothered with vaginal burning, itching or discharge? (0, 1, 2 or 3)      
      MEN:  Do you have burning, itching or discharge from the penis? (0, 1, 2 or 3)
7.   Are you bothered by burning, itching or tearing of your eyes? (0, 1, 2 or 3)

Score     0-3   =   FRD unlikely
Score     4-9   =   FRD probable
Score     10-21  =   FRD almost certain

Literature Cited:

Click on the attached PDF to download the full text article.

Effectiveness of nystatin in polysymptomatic patients. A randomised, double-blind trial with nystatin versus placebo in general practice. 
Heiko Santelmann,
Even Lærum, Jørgen Rønneviga, and Hans E Fagertunb,
Department of General Practice and Community Medicine, University of Oslo, 0317 Oslo,
a Alpharma AS, 0212 Oslo and b Parexel Medstat AS, 2001 Lillestrøm, Norway.

Keywords: candida symptoms, FRDQ-7, fungal questionnaire, fungal related disease questionnaire, Santelmann et al. (2001),

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