The Library
The Ultimate On-line Candida Resource
Glossary    Contact Us
 
   
Browse by Category
Your Are Here >> Library Home > Treatments > Probiotics (As Candida Treatment) > Pharmaceutical Probiotics for the Treatment of Anaerobic and Other Infections

Back

We'd love to hear from you - the Candida Library is for you. Let us know if you have any suggestions, ideas or feedback. Click here to email us.

Pharmaceutical Probiotics for the Treatment of Anaerobic and Other Infections

Pharmaceutical Probiotics for the Treatment of Anaerobic and Other Infections


L. V. McFarland and G. W. Elmer. Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, WA, 98102, U.S.A.


"Pharmaceutical probiotics have been used as alternative treatments or preventative therapies for a variety of clinical diseases. The overuse of antibiotics and emergence of multiple-antibiotic resistant pathogens has refocused clinical attention on the field of probiotics."



Abstract:

Pharmaceutical probiotics have been used as alternative treatments or preventative therapies for a variety of clinical diseases. The overuse of antibiotics and emergence of multiple-antibiotic resistant pathogens has refocused clinical attention on the field of probiotics. Anaerobic infections which seem to respond well to probiotics are infections which involve the disruption of normal microbial flora. Gastrointestinal infections (travelers' diarrhea, antibiotic-associated diarrhea,Clostridium difficiledisease, rotavirus diarrhea) have been studied using the following pharmaceutical probiotics:Saccharomyces boulardii, Lactobacillus caseiGG,Lactobacillus acidophilus, Lactobacillus bulgaricus, Bifidobacterium bifidum, Streptococcus thermophilusandEnterococcus faecium. Vaginitis has been experimentally studied usingL. acidophilusandL. caseiGG. The efficacy, safety and mechanisms of action of these various probiotics are reviewed. Requirements for drug approval are similar for biologic probiotics and new drug entities and these requirements involve preclinical tolerability studies, pharmacokinetic studies and large, well-controlled blinded clinical trials.


Full Article:

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6W9T-45MFNF0-F&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=f9c237bb1ef2c0e4304b5c4a2cac9862




Keywords: probiotic Anaerobic infections diarrhea Vaginitis alternative treatments

Rate This Article:

Related Articles

Antibiotics for Treatment of Acute Respiratory Tract Infections
Antibiotics for Treatment of Acute Respiratory Tract...

Probiotics: a role in the treatment of intestinal infection and inflammation?
Probiotics: a role in the treatment of intestinal...

Probiotic rich- fermented milk may reduce infections in the eldery
Improvement of nutritional status and incidence of...