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Undecylenic Acid Definition

Undecylenic Acid Molecular Structure
Undecylenic acid (10-undecenoic acid), is an eleven-carbon monounsaturated fatty acid, C11H20O2 (the antifungal properties of a medium chain fatty acid increases as the chain lengthens and peaks at 11 - caprylic acid contains only 8 carbon chains). Undecylenic acid is a naturally occurring fatty acid found in the castor bean and also as a product of human sweat glands.

Castor oil is a natural plant oil obtained from the seed of the castor plant. The castor seed, or
Castor Beans
bean, is the source of numerous economically important products as one of the world's most important industrial oils, and was one of the earliest commercial products. Castor beans have been found in ancient Egyptian tombs dating back to 4000 B.C. According to the Ebers Papyrus, an Egyptian medical text from 1500 B.C., Egyptian doctors used castor oil to protect the eyes from irritation. Castor oil has been used medicinally in the United States since the days of the pioneers.

Unlike bacteria, both fungi and humans are eukaryotes. Thus fungal and human cells are similar at the molecular level. This means it is more difficult to find a weakness in fungi to attack that does not also exist in human cells - so, if you attack the fungus, you may also attack the human cells the fungus lives on. Consequently, there are often side-effects to some of these drugs. Some of the drug's side-effects can be life-threatening.

The principle sterols in the fungal cell membrane is ergosterol. Some substances change the transition temperature (Tg) of the cell membrane, thereby placing the membrane in a less fluid, more crystalline state.

Definition from: http://www.absoluteastronomy.com/topics/Antifungal_drug


Keywords: undecylenic acid undecenoic acid 10-undecenoic acid C11H20O2 antifungal fatty acid castor bean oil Egyptian medicine sterols ergosterol sweat glands Beginner

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